Tesamorelin

A20-5010 · Weight Management & Metabolic

What labs study it for

Growth-hormone research. Labs use it to switch on the receptor that tells the pituitary gland to release growth hormone, in order to study that signalling chain in cells and animal models.

What this compound is

Tesamorelin is a synthetic 44-amino-acid analogue of growth-hormone-releasing hormone, modified at one end with a trans-3-hexenoyl group to resist enzymatic breakdown. Laboratories use it as a defined agonist tool for studying the GHRH receptor and the growth-hormone axis. Tesamorelin is approved as a drug product in the United States under a different brand name; the material supplied here is a laboratory reagent and is not that product.

Tesamorelin. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.

3D structure

Carbon in orange, nitrogen blue, oxygen red, sulfur yellow. Formula C221H366N72O67S.

Computed 3D model, not a measured structure. Drag to rotate · scroll to zoom.

Structure from PubChem CID 16137828, with 3D coordinates computed from it.

Family

All families →

GHRH analogues

All copy the same natural hormone and hit the same receptor.

Growth-hormone-releasing hormone is a 44-amino-acid hormone made in the hypothalamus. It binds the GHRH receptor on the pituitary, which is the switch for growth-hormone release. Each compound in this family is a version of that hormone, differing in how much of the sequence is kept and how it is protected from enzymes. Sermorelin keeps the first 29 residues — the shortest piece that still activates the receptor. Tesamorelin keeps all 44 and adds a chemical group at one end to slow breakdown. CJC-1295 DAC adds a group that latches onto albumin in blood, extending its life from minutes to days.

Fields of study

GHRH receptor pharmacology
Growth-hormone axis models

Specifications

Catalog number	A20-5010
CAS number	218949-48-5
Molecular formula	C221H366N72O67S
Molecular weight	5135.90 g/mol
Purity (HPLC)	≥ 99.0 %
Physical form	Lyophilized powder
Storage	-20 C, desiccated, protected from light
PubChem record	CID 16137828

Reference information for laboratory research only — not for human or veterinary use.