Sermorelin

A20-5030 · Muscle Growth & Performance

What labs study it for

Growth-hormone research. Labs use it as a standard reference signal for the growth-hormone-releasing receptor, a baseline to compare other compounds against.

What this compound is

Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of growth-hormone-releasing hormone, the shortest fragment that retains full receptor activity. Laboratories use it as a reference GHRH-receptor agonist in endocrine studies. Sermorelin was formerly marketed as an approved drug product in the United States; the material supplied here is a laboratory reagent and is not that product.

Sermorelin. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.

3D structure

Carbon in orange, nitrogen blue, oxygen red, sulfur yellow. Formula C149H246N44O42S.

Computed 3D model, not a measured structure. Drag to rotate · scroll to zoom.

Structure from PubChem CID 16132413, with 3D coordinates computed from it.

Family

All families →

GHRH analogues

All copy the same natural hormone and hit the same receptor.

Growth-hormone-releasing hormone is a 44-amino-acid hormone made in the hypothalamus. It binds the GHRH receptor on the pituitary, which is the switch for growth-hormone release. Each compound in this family is a version of that hormone, differing in how much of the sequence is kept and how it is protected from enzymes. Sermorelin keeps the first 29 residues — the shortest piece that still activates the receptor. Tesamorelin keeps all 44 and adds a chemical group at one end to slow breakdown. CJC-1295 DAC adds a group that latches onto albumin in blood, extending its life from minutes to days.

Fields of study

GHRH receptor pharmacology
Endocrine signalling models

Specifications

Catalog number	A20-5030
CAS number	86168-78-7
Molecular formula	C149H246N44O42S
Molecular weight	3357.90 g/mol
Purity (HPLC)	≥ 99.0 %
Physical form	Lyophilized powder
Storage	-20 C, desiccated, protected from light
PubChem record	CID 16132413

Reference information for laboratory research only — not for human or veterinary use.