Catalog / A20-1210
Research use only — not for human or veterinary use
KPV
Inflammation Support
What this compound is
KPV is a peptide of just three amino acids: lysine, proline and valine. The sequence is the tail end (residues 11-13) of alpha-melanocyte-stimulating hormone, a signalling molecule involved in pigmentation and inflammatory regulation. Because it is the smallest active fragment, laboratories use it as a probe for melanocortin-related inflammatory signalling in cultured cells and in animal models of mucosal inflammation, without the pigmentation activity of the full hormone. It is not approved for any medical use.
Studied in
- Melanocortin signalling
- Inflammatory pathway models
- Mucosal biology
Chemical description
KPV. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.
Specifications
| Catalog number | A20-1210 |
|---|---|
| Type | Inflammation Support |
| CAS number | 67727-97-3 |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.43 g/mol |
| Sequence | KPV |
| Purity (HPLC) | ≥ 99.0 % |
| Physical form | Lyophilized powder |
| Storage | -20 C, desiccated, protected from light |
Literature
Published sources, listed for reference. Findings are not summarized here — follow the citation.
- Dalmasso G, et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. 2008;134(1):166-78. PMID 18061177
Documents
Certificate of analysis
No lot certificate published for this compound yet. Contact support with the lot number on your vial.
Safety data sheet
Not yet published for this compound.