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Calm & Focus
Selank
A20-1180 · Cognitive & Focus & Mood
What labs study it for
Brain-chemistry and behaviour research. Labs use it in rodent studies of GABA (the brain's main calming messenger) and other brain-signalling systems.
What this compound is
Selank is a synthetic peptide of seven amino acids. It joins the sequence of tuftsin, a short fragment of an antibody molecule, to the same proline-glycine-proline tail used in Semax to slow enzymatic breakdown. Laboratories use it in rodent behavioural and neurochemical studies, particularly of GABAergic and monoamine signalling. Like Semax it comes from Russian research and is licensed for clinical use there; it has not been approved by the FDA or the EMA.
Selank. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.
3D structure
Carbon in orange, nitrogen blue, oxygen red, sulfur yellow. Formula C33H57N11O9.
Structure from PubChem CID 11765600, with 3D coordinates computed from it.
Family
All families →PGP-stabilised neuropeptides
Two unrelated fragments given the same protective tail.
This is a design family rather than a biological one, and it is a neat piece of chemistry. Short peptides are broken down quickly by enzymes in the body. Researchers in Russia addressed this by attaching a proline-glycine-proline tail, which resists that breakdown. Semax applies it to a fragment of adrenocorticotropic hormone; Selank applies it to tuftsin, a fragment of an antibody molecule. The starting fragments are unrelated — the shared tail is what makes them siblings.
Fields of study
- Neuropeptide pharmacology
- GABAergic signalling
- Rodent behavioural models
Specifications
| Catalog number | A20-1180 |
|---|---|
| CAS number | 129954-34-3 |
| Molecular formula | C33H57N11O9 |
| Molecular weight | 751.90 g/mol |
| Purity (HPLC) | ≥ 99.0 % |
| Physical form | Lyophilized powder |
| Storage | -20 C, desiccated, protected from light |
| PubChem record | CID 11765600 |
Reference information for laboratory research only — not for human or veterinary use.