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Skin Repair
GHK-Cu
A20-2010 · Skin & Beauty & “Glow”
What labs study it for
Skin and connective-tissue research. Labs add it to cultured skin cells (fibroblasts) to study how cells build collagen and the other structural proteins that hold tissue together, and how copper is carried into cells.
What this compound is
GHK-Cu is a copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The peptide occurs in human plasma and binds copper(II) ions with high affinity, which is what the Cu in the name denotes. Laboratory work uses it as a defined copper-delivery tool in cell-culture studies of extracellular matrix components such as collagen, and in connective tissue models. It is not approved for any medical use.
GHK-Cu. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.
3D structure
Carbon in orange, nitrogen blue, oxygen red, sulfur yellow. Formula C14H23CuN6O4+.
Structure from PubChem CID 71587328, with 3D coordinates computed from it.
Family
All families →Metal-binding peptides
A peptide defined as much by the metal it carries as by its sequence.
Some short peptides bind metal ions tightly enough that the complex, not the peptide alone, is the molecule of interest. GHK is three amino acids found in human plasma; it binds copper(II) with high affinity, and the resulting complex is what laboratories study in extracellular-matrix and connective-tissue work. Written GHK-Cu, the suffix denotes the bound copper.
Fields of study
- Extracellular matrix models
- Copper transport
- Connective tissue biology
Specifications
| Catalog number | A20-2010 |
|---|---|
| CAS number | 89030-95-5 |
| Molecular formula | C14H22CuN6O4 |
| Molecular weight | 401.90 g/mol |
| Purity (HPLC) | ≥ 99.0 % |
| Physical form | Lyophilized powder |
| Storage | -20 C, desiccated, protected from light |
| PubChem record | CID 71587328 |
Reference information for laboratory research only — not for human or veterinary use.