Weight Management & Metabolic

What labs study it for

Metabolism and hormone-receptor research. Labs use it to study how one molecule can switch on three different hormone receptors at once (GLP-1, GIP and glucagon), and how that signalling plays out in cell and animal models of energy balance.

What this compound is

Retatrutide is a synthetic investigational peptide designed as a single molecule acting at three receptors: GIP, GLP-1 and glucagon. It is a long synthetic chain carrying a fatty-acid modification that extends its half-life. It is investigational, has not been approved by any regulatory authority anywhere in the world, and is supplied strictly as a laboratory reagent.

Chemical description

Retatrutide. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.

Studied in

Receptor pharmacology · Incretin signalling · Metabolic regulation models

What labs study it for

Growth-hormone research. Labs use it to switch on the receptor that tells the pituitary gland to release growth hormone, in order to study that signalling chain in cells and animal models.

What this compound is

Tesamorelin is a synthetic 44-amino-acid analogue of growth-hormone-releasing hormone, modified at one end with a trans-3-hexenoyl group to resist enzymatic breakdown. Laboratories use it as a defined agonist tool for studying the GHRH receptor and the growth-hormone axis. Tesamorelin is approved as a drug product in the United States under a different brand name; the material supplied here is a laboratory reagent and is not that product.

Chemical description

Tesamorelin. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.

Studied in

GHRH receptor pharmacology · Growth-hormone axis models

What labs study it for

Mitochondria and cell-energy research. Labs use it to study how mitochondria, the cell's power plants, send signals to the rest of the cell, including the AMPK energy-sensing pathway.

What this compound is

MOTS-c is a peptide of sixteen amino acids, unusual in its origin: it is encoded not by the cell nucleus but by mitochondrial DNA, within the 12S ribosomal RNA gene. Peptides of this kind are called mitochondrial-derived peptides, and MOTS-c was among the first identified. Laboratory research examines its role in AMPK signalling and folate-methionine metabolism, and its behaviour as a signalling molecule between mitochondria and the rest of the cell, principally in cell culture and rodent models.

Chemical description

MOTS-c. Supplied lyophilized. Lot-specific HPLC and MS documentation accompanies each unit.

Studied in

Mitochondrial signalling · AMPK pathway · Metabolic regulation models